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Your healthcare provider can help customize a treatment schedule based on your specific needs and how you respond to the initial treatment

For instance, accumulated succinate acts as a competitive inhibitor of -KGdependent dioxygenases, including the ten-eleven translocation (TET) family of DNA demethylases and Jumonji C domain-containing (JMJD) family histone demethylases, thereby promoting global DNA hypermethylation and transcriptional silencing [51]